Often asked: How To Give Methotrexate Injection For Ectopic Pregnancy?

Where do you inject methotrexate for ectopic pregnancy?

We will inject the methotrexate into a muscle in your buttocks, which may be uncomfortable. Usually one dose will be enough but, very rarely, a second dose might be needed.

How long does it take for methotrexate injections to work for ectopic pregnancy?

When this happens, we know that the medication has worked. This can take at least 4-6 weeks.

What happens after methotrexate injection for ectopic pregnancy?

About two to seven days after the injection you will probably have some pain in your lower abdomen. It should not be severe and lasts four to 12 hours. You can also expect to have vaginal bleeding which is light or like a period. This lasts a few days but you may have a brown discharge for two to three weeks.

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How much methotrexate do they give for ectopic pregnancy?

It’s given by injection, and usually just 1 dose is given. You will need to have blood tests to monitor the level of pregnancy hormone in your blood. The methotrexate will stop the pregnancy and the level of pregnancy hormone in your blood should decrease over 2 to 4 days.

What happens if you get pregnant after methotrexate?

Methotrexate, a common treatment for RA, can cause birth abnormalities if either partner takes the drug during conception or pregnancy. Women who become pregnant while taking methotrexate should stop taking methotrexate and contact a doctor as soon as possible.

How soon after methotrexate will I get my period?

Most find that their period arrives sometime around week six or seven after surgery, or, if treated without surgery, at some time in the four weeks after their hCG levels have fallen to below 100 mIU/mL. Before you can have a period, you would usually have to ovulate.

What can I expect after methotrexate injection?

Methotrexate is given by injection. After treatment, you may have mild abdominal pain or cramping. Some women also have nausea and vomiting, diarrhea, or fatigue. There are some cases when you can’t use methotrexate.

Can your tube rupture after methotrexate?

There is still around a one in 14 chance of your fallopian tubes splitting open (rupture) after medical treatment with methotrexate, even if your hCG levels are going down. Therefore, be aware of the potential symptoms of a rupture and be ready to call an ambulance if you think a rupture has occurred.

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Why do you have to wait 3 months after methotrexate?

Some healthcare providers suggest waiting 1 to 3 months after stopping methotrexate to ensure the medication has been cleared from the body.

What should I avoid after methotrexate for ectopic pregnancy?

Yes, during treatment with methotrexate you should avoid the following:

  • Heavy exercise.
  • Sexual intercourse.
  • Alcohol.
  • Vitamins and foods that contain folic acid, including fortified cereal, enriched bread and pasta, peanuts, dark green leafy vegetables, orange juice, and beans.

What happens if methotrexate doesn’t work for ectopic pregnancy?

If methotrexate therapy doesn’t work, surgery is the next step. It’s also the only option for women with high hCG levels, severe symptoms, and ruptured or damaged fallopian tubes. You may have laparoscopic surgery that involves a very small cut and a tiny camera.

How long stop folic acid after methotrexate?

Avoid taking these medicines during methotrexate treatment and for one week after your treatment has finished. Products containing folic acid, including multivitamins, can reduce the effectiveness of treatment with methotrexate.

How fast do hCG levels drop after methotrexate?

If single-dose therapy is used, serum hCG concentrations are measured on the day of administration and on days 4 and 7 after administration. hCG levels frequently increase between the day of administration and day 4; however, there should be a 15% or greater drop in hCG between days 4 and 7.

What should you avoid while taking methotrexate?

What should I avoid while taking methotrexate? Avoid drinking alcohol. It may increase your risk of liver damage. Do not receive a “live” vaccine while using methotrexate, or you could develop a serious infection.

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What is the success rate of methotrexate?

According to the statistics in the literature, the success rate of MTX treatment varies from 65 to 95%, with a mean rate of 82%, and the fertility rate with delivery after medical treatment for ectopic pregnancy is 67–80.7%, which is not less than that after conservative and radical surgery [4,5,6,7], [8,9,10,11,12].

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