FAQ: What Does Methotrexate Do For Ectopic Pregnancy?

What happens after methotrexate for ectopic pregnancy?

About two to seven days after the injection you will probably have some pain in your lower abdomen. It should not be severe and lasts four to 12 hours. You can also expect to have vaginal bleeding which is light or like a period. This lasts a few days but you may have a brown discharge for two to three weeks.

How long does methotrexate take to work for ectopic?

When this happens, we know that the medication has worked. This can take at least 4-6 weeks.

How effective is methotrexate for ectopic pregnancy?

According to the statistics in the literature, the success rate of MTX treatment varies from 65 to 95%, with a mean rate of 82%, and the fertility rate with delivery after medical treatment for ectopic pregnancy is 67–80.7%, which is not less than that after conservative and radical surgery [4,5,6,7], [8,9,10,11,12].

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How did you feel after methotrexate for ectopic?

The most common side effect of methotrexate is some cramping belly pain. This pain usually occurs in the first one to two days of treatment. You may also start or continue to see vaginal bleeding or spotting, or have other GI side effects, like nausea, vomiting, or indigestion.

How soon after methotrexate will I start bleeding?

A few days after the injection, it is usual to begin to bleed and this bleeding can last between a few days and up to 6 weeks. It is usual to have some discomfort and pain initially but as long as this is not severe.

How soon after methotrexate will I get my period?

Most find that their period arrives sometime around week six or seven after surgery, or, if treated without surgery, at some time in the four weeks after their hCG levels have fallen to below 100 mIU/mL. Before you can have a period, you would usually have to ovulate.

How soon after methotrexate can I get pregnant?

However, due to general concern rather than actual risks, some healthcare providers recommend that men wait at least 3 months after stopping methotrexate before trying to conceive.

What can I expect after methotrexate injection?

Methotrexate is given by injection. After treatment, you may have mild abdominal pain or cramping. Some women also have nausea and vomiting, diarrhea, or fatigue. There are some cases when you can’t use methotrexate.

Can your tube rupture after methotrexate?

There is still around a one in 14 chance of your fallopian tubes splitting open (rupture) after medical treatment with methotrexate, even if your hCG levels are going down. Therefore, be aware of the potential symptoms of a rupture and be ready to call an ambulance if you think a rupture has occurred.

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How fast do hCG levels drop after methotrexate?

If single-dose therapy is used, serum hCG concentrations are measured on the day of administration and on days 4 and 7 after administration. hCG levels frequently increase between the day of administration and day 4; however, there should be a 15% or greater drop in hCG between days 4 and 7.

What should you avoid while taking methotrexate?

What should I avoid while taking methotrexate? Avoid drinking alcohol. It may increase your risk of liver damage. Do not receive a “live” vaccine while using methotrexate, or you could develop a serious infection.

What should I avoid after methotrexate for ectopic pregnancy?

Yes, during treatment with methotrexate you should avoid the following:

  • Heavy exercise.
  • Sexual intercourse.
  • Alcohol.
  • Vitamins and foods that contain folic acid, including fortified cereal, enriched bread and pasta, peanuts, dark green leafy vegetables, orange juice, and beans.

How long stop folic acid after methotrexate?

Avoid taking these medicines during methotrexate treatment and for one week after your treatment has finished. Products containing folic acid, including multivitamins, can reduce the effectiveness of treatment with methotrexate.

How do you know if methotrexate is working?

X-rays of your affected joints should indicate that existing bone or joint damage is not getting worse. Some laboratory values may also improve. It usually takes three to six weeks after starting methotrexate to see improvement. It may take as long as 12 weeks to feel the maximum effect.

Where do they inject methotrexate for ectopic pregnancy?

To treat ectopic pregnancy, methotrexate is typically given as an injection (a shot) into a muscle. This often takes place in a hospital emergency room. In some cases, a second or third injection is necessary in the weeks after the first injection. Most ectopic pregnancies occur in a fallopian tube.

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